RNDr. Jan Hošek, Ph.D.

 

Education and academic qualifications

 

  • 2006:  Degree Mgr.- Faculty of Science,  Masaryk University, Brno,  programme Molecular Biology and Genetic
  • 2008:  Degree RNDr.- Faculty of Science,  Masaryk University, Brno,  programme Molecular Biology and Genetic
  • 2011: Degree Ph.D.- Faculty of Science,  Masaryk University, Brno, programme General and Molecular Genetics

 

 

Professional experience

 

 

  • IX/2011 - so far:  Junior researcher at the Regional Centre of Advanced Technologies and Materials, Olomouc
  • II/2011 - so far: Research assistant, Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno
  • IX/2006 - I/2011: Assistant, Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno
  • IX/2003 - XII/2005: Laboratory technician, Veterinary research institute, Brno, Department of Food and feed safety

 

 

Teaching activities

 

  • Guarantor of 4 subjects at Faculty of Pharmacy, UVPS, Brno:
  • Supervisor of undergraduated and post-graduated students at Faculty of Pharmacy, UVPS, Brno
    • Methods of Molecular Biology (Czech/English)
    • Biotechnology of Drugs, practical classe (Czech/English)

 

 

Research activities

  • Molecular biology – especially gene expression and cell culture experiments
  • Molecular immunology – especially inflammation and apoptosis

 

Professional stays abroad

 

  • V/2012 - IX/2012: Research internship at Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Italy, prof. Chiara Bolego’s group
  • XI/2011: Research internship at the Department of Biology, American University of Beirut, Lebanon, prof. Rabih Talhouk’s group
  • VII/2007 - IX/2007: Summer internship student programme, Protein Phosphorylation Unit, University of Dundee, Scotland, Dr. Kei Sakamoto’s group

 

Major publications

 

  • HOŠEK, Jan, BARTOS, Milan, CHUDÍK, Stanislav, DALL´ACQUA, Stefano, INNOCENTI, Gabbriella, KARTAL, Murat, KOKOŠKA, Ladislav,  KOLLÁR, Peter, KUTIL, Zsofia, LANDA, Přemysl, MAREK, Radek, ZÁVALOVÁ, Veronika, ŽEMLIČKA, Milan, and  ŠMEJKAL, Karel. Natural Compound Cudraflavone B Shows Promising Anti-inflammatory Properties in Vitro. J. Nat. Prod. 2011, 74 (4): 614–619. ISSN 0163-3864, IF(2011) = 3,128
  • TRÁVNÍČEK, Zdeněk, ŠTARHA, Pavel, VANČO, Ján, ŠILHA, Tomáš, HOŠEK, Jan, SUCHÝ Jr., Pavel, PRAŽANOVÁ, Gabriela. Anti-inflammatory Active Gold(I) Complexes Involving 6-Substituted-Purine Derivatives. J. Med. Chem. 2012, 55 (10): 4568-4579. ISSN 0022-2623. IF(2011) = 5,248
  • PĚNČÍKOVÁ, Kristýna, KOLLÁR, Peter, MÜLLER ZÁVALOVÁ, Veronika, TÁBORSKÁ, Eva, URBANOVÁ, Jana, HOŠEK, Jan. Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line. Phytomedicine. 2012, 19 (10): 890-895. ISSN 0944-7113. IF(2011) = 3,268
  • TRÁVNÍČEK, Zdeněk, VANČO, Ján, HOŠEK, Jan, BUCHTÍK, Roman, DVOŘÁK, Zedněk. Cellular responses induced by Cu(II) quinolinonato complexes in human tumor and hepatic cells. Chem. Cent. J. 2012, 6: 160. ISSN 1752-153X. IF(2011) = 3,281