PharmDr. Aleš FRANC, Ph.D.

 

Education and academic qualifications

  • 2010: Ph.D. in Pharmaceutical Technology, University of Veterinary and Pharmaceutical Sciences Brno
  • 2004: PharmDr. in Pharmaceutical Technology, University of Veterinary and Pharmaceutical Sciences Brno
  • 1994: Attestation in Technological Pharmacy, ILF Prague
  • 1990: Mgr. in Technological Pharmacy and General Pharmacy, Faculty of Pharmacy, Charles University in Prague

 

Professional experience

  • 2010 – Assistant Professor, University of Veterinary and Pharmaceutical Sciences Brno
  • 1992 – 2009: Scientific Researcher, Pliva – Barr, Brno
  • 1990 - 1991: Pharmaceutical Assistant, Pharmaceutical Service, Prachatice

 

Teaching activities

  • Master course of pharmacy: lecturer - Medical forms and Biopharmacy. Tutor of diploma and rigorous thesises, postgraduate students supervisor in Pharmaceutical Technology.
  • Tutor of postgraduate students.(UVLF Košice)

 

Research activities

  • Preparation of dosage forms with poorly soluble and hardly absorbable APIs; formulation of dosage forms with controlled release, direct compression of tablets with low content of APIs.

 

Professional stays abroad

  • 2002-2008: Transfers of pharmaceutical technologies to Pliva Zagreb (Croatia), Zydus and Emcure (India), Elaiapharm (France)
  • 1999: Coating School, Colorcon, Dartford, UK

 

 

Other academic activities, research projects, grants

  • 301/2017/FAF. Hodnocení tabletovin a tablet získaných ze společně zpracovaných směsí. University of Veterinary and Pharmaceutical Sciences Brno.

  • TA04011060 Technologie pro nový kolorimetrický trubičkový biosenzor inhibitorů cholinesteráz v ovzduší i v kapalných vzorcích. Technologická agentura České republiky (TA ČR).
  • 55/2014/FaF Tvorba biorelevantní disoluční metody pro kontrolu kvality tablet s obsahem warfarinu. University of Veterinary and Pharmaceutical Sciences Brno.
  • 61/2014/FaF Vývoj pH závislé disoluční metody pro kontrolu uvolňování glukosy z pelet s řízeným uvolňováním pro prevenci hypoglykémie. University of Veterinary and Pharmaceutical Sciences Brno.
  • 14479/2013, Preparation of dosage forms with controlled release of glucose to prevention of hypoglycemic states. Ministry of Health of the Czech Republic.
  • 39 /2011/FaF Safety increasing of oral solid dosage drugs with narrow therapeutic index. University of Veterinary and Pharmaceutical Sciences Brno.
  • FB-CV/09/2000,  Léčiva k prevenci a léčbě virových onemocnění a nemocí centrálního nervového systému. MPO.
  • PZ - Z2/29, Nová léčiva pro terapii nádorových onemocnění. MPO.

 

Non-university activities

  • Czech Pharmaceutical Society  –  The Section of Drug Technology, Scientific Secretary (since 2011)

 

Major publications

            Selected Articles

  • Lukasova, Ivana; Muselik, Jan; Franc, Ales; et al. Factor analysis in optimization of formulation of high content uniformity tablets containing low dose active substance. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES: 2017 (109) 541-547.
  • Zeman, Jiri; Vetchy, David; Franc, Ales; et al. The development of a butyrylcholinesterase porous pellet for innovative detection of cholinesterase inhibitors EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES: 2017 (109) 548-555.
  • Matejova, Iveta; Faldyna, Martin; Modra, Helena; Franc, Aleš et al. Effect of T-2 toxin-contaminated diet on common carp (Cyprinus carpio L.) FISH & SHELLFISH IMMUNOLOGY: 2017 (60) 458-465.
  • Franc, Ales; Muselik, Jan; Sabadkova, Dana; et al.Preparation of pellets with controlled release of glucose as prevention of hypoglycaemia in paediatric patients EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES: 2015 (75) 72-80.
  • Matejova, Iveta; Modra, Helena; Blahova, Jana; et al. The Effect of Mycotoxin Deoxynivalenol on Haematological and Biochemical Indicators and Histopathological Changes in Rainbow Trout (Oncorhynchus mykiss) BIOMED RESEARCH INTERNATIONAL (2014).

 

            Selected Patents

  • FRANC, A., SOVA, P. Pharmaceutical composition for oral administration. PLIVA LACHEMA AS [CZ] AU2007262493; 2007-12-27
  • FRANC, A., ŽALUDEK B., et. al. Preparation and composition of a solid dosage form containing tacrolimus and/or sirolimus. Inventor:  PLIVA ISTRAZIVANJE I RAZVOJ D [HR] WO2007091059; 2007-08-16
  • FRANC, A., SOVA, P.Pharmaceutical composition for rectal or vaginal application comprising a platinum complex. EP1809274; 2007-07-25
  • FRANC, A., ŽALUDEK, B. Pharmaceutical composition containing ribavirin as active substance and method of manufacturing thereof. PLIVA LACHEMA AS [CZ] EP1617824; 2006-01-2.
  • FRANC, A., ŽALUDEK, B. Oral solid instant-release dosage forms comprising finasteride and an anionic surfactant - methods of manufacturing thereof.  PLIVA LACHEMA AS [CZ] EP1694336; 2006-08-30
  • FRANC, A., ŽALUDEK B., et. al.   Method of producing dosage units of a solid drug form containing warfarin sodium salt as active component. PLIVA LACHEMA AS [CZ] WO2005034919; 2005-04-21