Assoc. Prof. Mgr. Jan Muselík, Ph.D.

 

Education and academic qualifications

  • 2013: Assoc. Prof. in Pharmaceutical chemistry, University of Veterinary and Pharmaceutical Sciences Brno
  • 2005: Ph.D. in Pharmaceutical chemistry, University of Veterinary and Pharmaceutical Sciences Brno
  • 2000: Faculty of Science, Masaryk University Brno, specialization in analytical chemistry

 

Professional experience

  • 2013-: Associate Professor, Department of Pharmaceutics, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
  • 2005-2013 Assistant Professor, Department of Pharmaceutics, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
  • 2004-2005 Assistant, Department of Pharmaceutics, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
  • 2001-2004 Assistant, Department of Chemical Drugs, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

 

Teaching activities

  • Master course of pharmacy: lecturer - Instrumental analytical methods in pharmaceutical technology. Tutor of diploma and rigorous theses, postgraduate students supervisor in pharmaceutical technology.

 

Research activities

  • Separation techniques, especially liquid chromatography (HPLC, SEC) and spectral methods (UV/Vis, FT-IR, FT-NIR). The main scope of scientific work is the development of new methods and their application in the analysis of dosage forms and natural materials.

 

Professional stays abroad

  • 2006: Ankara University, Turkey
  • 2003: Universidad de Salamanca, Spain
  • 1999: Universidad Autónoma de Barcelona, Spain

Other academic activities, research projects, grants

  • 55/2014/FaF, Development of biorelevant dissolution methods for monitoring quality of tablets containing warfarin. University of Veterinary and Pharmaceutical Sciences Brno.
  • 61/2014/FaF, Development of pH-dependent dissolution method for controlling the release of glucose from pellets with controlled release to prevent hypoglycemia. University of Veterinary and Pharmaceutical Sciences Brno.
  • 14477/2013, Modern Dosage Form for the Therapy of Oral Candidoses, Ministry of Health of the Czech Republic.
  • 14479/2013, Preparation of dosage forms with controlled release of glucose to prevention of hypoglycaemic states, Ministry of Health of the Czech Republic.
  • TA01010244, Modified materials for chronic and acute wound treatment and surgical infection control in healthcare, Technology Agency of the Czech Republic.
  • 2474/2011/F1/a, Innovation of practical exercises from the Instrumental analytical methods in pharmaceutical technology, University Development Fund of the Czech Ministry of Education, Youth and Sports.
  • 39/2011/FaF, Safety increasing of oral solid dosage grugs with narrow therapeutic index, Veterinary and Pharmaceutical University.
  • 2A-1TP1/073, New pharmaceutical products based on polysaccharides, Ministry of Industry and Trade.
  • OE235, The development of the multifunctional semisolid preparations from natural products, Ministry of Education, Youth and Sports.

 

Major publications

  • MUSELÍK, J., FRANC A., DOLEŽEL, P., GONĚC, R., KRONDLOVÁ, A., LUKÁŠOVÁ, I.: Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. Acta. Pharm. 2014 (64), 355-367. IF2013 = 1.025.
  • DOLEŽEL P., MUSELÍK J.: The Use of Raman Spectroscopy in the Study of Mixing Mechanisms for Powder Blends. Chem. Listy 2014 (108), 167-171. IF2013 = 0.196.
  • ZIMOVA, L., VETCHY, D., MUSELIK, J., STEMBIREK, J.: The development and in vivo evaluation of a colon drug delivery system using human volunteers. Drug Deliv., 2012, 19 (2), 81-89. ISSN: 1071-7544, IF2011=1,456
  • DVOŘÁČKOVÁ, K., RABIŠKOVÁ, M., GAJDZIOK, J., VETCHÝ, D., MUSELÍK, J.,BERNATONIENE, J., BAJEROVÁ, M., DROTTNEROVÁ, P. Coated capsules for drug targeting to proximal and distal part of human intestine. Acta Pol. Pharm. Drug Res., 2010, 67 (2), 191-199. ISSN: 0001-6837, IF2010= 0,465
  • GAJDZIOK, J., BERNATONIENE, J., MUSELÍK, J., MASTEIKOVÁ, R., DVOŘÁČKOVÁ, K., PETKEVICIUTE, Z., LAZAUSKAS, R., KALVENIENE, Z., BERNATONIENE, R.: The evaluation of formulations for the preparation of new formula pellets. Pharm. Dev. Technol., 2011, 16 (5), 520-528.  ISSN: 1083-7450, IF2011=1,363
  • BERNATONIENE, J., MASTEIKOVA, R., DAVALGIENE, J., PECIURA R., GAURYLIENE, R., BERNATONIENE, R., MAJIENE, D., LAZAUSKAS, R., CIVINSKIENE, G., VELZIENE, S., MUSELIK, J., CHALUPOVA, Z.:  Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activity. J. Med. Plants. Res., 2011 5 (6), 868-877. ISSN: 1996-0875
  • MUSELÍK, J., DVOŘÁČKOVÁ, K., KREJČOVÁ, K., RABIŠKOVÁ, M., PAZOUREK, J., MARTON, S., DRAČKOVÁ, M., VORLOVÁ, L.:  Pellet coating thickness determination by near-infrared reflectance spectroscopy: comparison of two reference methods. Curr. Pharm. Anal., 2010, 6 (4), 225-233. ISSN: 1573-4129, IF2010=1,710
  • ZIMA, A., HOŠEK, J., TREML, J., MUSELÍK, J., SUCHÝ, P., PRAŽANOVÁ, G., LOPES, A., ŽEMLIČKA, M.: Antiradical and cytoprotective activities of several C-geranyl-substituted flavanones from Paulownia tomentosa Fruit. Molecules, 2010, 15 (9), 6035-6049. ISSN: 1420-3049, IF2010=1,988
  • DVOŘÁČKOVÁ, K., RABIŠKOVÁ, M., GAJDZIOK, J., VETCHÝ, D., MUSELÍK, J., BERNATONIENE, J., BAJEROVÁ, M., DROTTNEROVÁ, P.: Coated capsules for drug targeting to proximal and distal part of human intestine. Acta Pol. Pharm., 2010, 67 (2), 191-199. ISSN: 0001-6837, IF2010=0,465
  • DOLEŽEL, P., MUSELÍK, J., DVOŘÁČKOVÁ, K., ŠUSTOVÁ, K.: A study of the process of homogenization of powder mixtures using NIR spectroscopy. Čes. Slov. Farm., 2010, 59 (6), 263-271. ISSN: 12107816
  • MUSELÍK, J., KREJČOVÁ, K., RABIŠKOVÁ, M., BARTOŠÍKOVÁ, A., DRAČKOVÁ, M., VORLOVÁ, L.: Determination of the Thickness of Tablet Coating by Near-Infrared Spectroscopy. Chem. Listy, 2010, 104 (1), 41-45. ISSN: 0009-2770, IF2010=0,620
  • DVOŘÁČKOVÁ, K., RABIŠKOVÁ, M., MASTEIKOVÁ, R., MUSELÍK, J., KREJČOVÁ, K.: Soluble filler as a dissolution profile modulator for slightly soluble drugs in matrix tablets. Drug Develop. Ind. Pharm., 2009, 35 (8), 930-940. ISSN: 0363-9045, IF2009=0,960
  • MUSELÍK, J., DVOŘÁČKOVÁ, K., RABIŠKOVÁ, M., BARTOŠÍKOVÁ, A., ROSENDORFOVÁ, M., DRAČKOVÁ, M., VORLOVÁ, L.: Determination of the coating thickness of HPMC hard capsules by near-infrared reflectance spectroscopy. Čes. Slov. Farm., 2009, 58 (4), 155-159. ISSN: 12107816
  • MUSELÍK, J., MASTEIKOVÁ, R., SUCHÝ, V., CHALUPOVÁ, Z., OSTRÁ, V.: Determination of the constituents of propolis of different geographical origin. Čes. Slov. Farm., 2009, 58 (4), 179-183. ISSN: 12107816
  • VANČO, J., MAREK, J., TRÁVNÍČEK, Z., RAČANSKÁ, E., MUSELÍK, J., ŠVAJLENOVÁ, O.: Synthesis, structural characterization, antiradical and antidiabetic activities of copper(II) and zinc(II) Schiff base complexes derived from salicylaldehyde and β-alanine. J. Inorg. Biochem., 2008, 102 (4), 595-605. ISSN: 0162-0134, IF2008=3,133