Prof. RNDr. Jozef Csöllei, CSc.



Prof. RNDr. Jozef Csöllei, CSc.


Born: 2. 11. 1950

Address: Oblá 44, 634 00 Brno, Czech Republic


Education and academic qualifications:

  • MSc.: Faculty of  Pharmacy, Comenius University, Bratislava, 1970 - 1975
  • RNDr. degrese: Department of  Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, 1977
  • CSc. degrese (equivalent to Ph.D.): Department of  Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, 1985
  • Associate Professor: Faculty of Pharmacy, Comenius University, Bratislava, specialization Pharmaceutical Chemistry,1991
  • Profesor: Faculty of Pharmacy, University of Veterinary and Pharmaceutical Science, Brno, specialization Pharmaceutical Chemistry, 2000


Teaching activities

Teacher, lecturer and researcher at Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Science.

Scientific coordinator and consultant:  diploma thesis (Mgr), postgradual thesis (PharmDr), postgradual students (PhD ).

Course supervisor of Medicinal Chemistry, Branch Board Chairman of postgraduate programmes of Medicinal Chemistry.



Research activities

His scientific research concentrates on the subject of the compound synthesis and the study the relation of the structure and effect of biologically active compounds affecting the cardiovascular system with focus on β-adrenolytic, antihypertensive and  β3-agonistic   activities.


Professional stays abroad

Department of  Medicinal Chemistry, Faculty of Life Sciences, University of Vienna, Austria
Phaculty of Pharmacy, University of Szeged, Hungary



Czech Pharmaceutical Society

Czech Chemical Society






Other academic activities, research projects, grants


Research Projects:


VZ MSM 163700003(co-solver): Preparation, evaluation, pre-clinical testing and drug formulation of new biologically active substances – potential drugs, affecting reactive forms of oxygen (1999-2004).

GA ČR 203/03/D182 (co-solver): Basic analytical rating, antioxidative and antiradical activity of newly synthesized substances with potential cardiovascular effect (2003-2005).

GA ČR 305/06/0863 (co-solver): Determination of the basic pharmacodynamic and pharmacokinetic parameters of newly synthesized ultrashort-acting betalytics (2006-2008).

VZ MSM 6215712403(co-solver: Active creation of health, yield and performance of the large animals (2005-2011).


Major publications

  1. Csöllei J., Borovanský A., Čižmárik J., Švec P., Račanská E., Tumová I.: Asymetrische dibasische Alkylesters der Alkoxycarbamidsären. Pharmazie 43, 609-610(1988)               
  2. Kettmann V., Csöllei J.: Structure of ethyl-[(2-hydroxy-3-isopropylamino)-propoxy]carbanilate hydrochloride. Acta Cryst. C45, 279 - 282 (1989)
  3. Račanská E., Csöllei J., Švec P.: Pharmacological evulation of new alkylesters of 4-[(2-hydroxy-3-alkylamino)-propoxy]phenylcarbamic acid with beta-adrenolytic properties. Pharmazie 45(11), 851 - 853 (1990)        
  4. Kettmann V., Csöllei J., Račanská E., Švec P.: Synthesis and structure-activity relationships of new beta-adrenoreceptor antagonists. Evidence for the electrostatic requirements for beta-adrenoreceptor antagonists. Eur. J .Med. Chem. 26, 843 - 851 (1991)    
  5. Ecker G., Chiba P., Hiutzler M., Schmid D., Visser K., Cordes H.P., Csöllei J., Seydel J.K. Schaper K.J.: " Structure -Activity Relationship Studies on Benzofurane Analogs of Propafenone-Type Modulators of Tumor Cell Multidmg Resistence". J.Med.Chem. 39, 4767-4774 (l 996)
  6. Račanská E., Kurfürst P., Csöllei J., Švec P.: Cardiovascular effects of newly synthetisized hybrid heteroarylaminoethanols. Acta Fac. Pharm. Univ. Comenianae 51, 182 - 191 (2004)
  7. Malík, I., Sedlárová, E., Csöllei, J., Andriamainty, F., Kurfürst, P., Vančo, J.: Synthesis, spectral description and lipophilicity parameters determination of phenylcarbamic acid derivatives with integrated N-phenylpiperazine moiety in the structure. Chem. Pap. 60(1), 42-47 (2006)
  8. Malík, I., Sedlárová, E., Csöllei, J., Andriamainty, F., Čižmárik, J.: Relationship between physicochemical properties, lipophilicity parameters and local anesthetic activity of dibasic esters of phenylcarbamic acid. Chem. Pap. 61(3), 206-213 (2007)
  9. Opatřilová, R., Jampílek, J., Raich, I., Kačerová, S., Havlíček, J., Pekárek, T., Dohnal, J., Csöllei, J.: Synthesis, Characterization and Physico-chemical Properties of New 2-(4-Arylpiperazine-1-yl)-1-(3-methylbenzofuran-2-yl)ethanoles as Potential Antihypertensive Agents.  Curr. Org. Chem. 2009, 13, (10), 965-975
  10. Otevřel, J., Mandelová, Z., Peško, M., Guo, J., KráĽová, K., Šeršen, F., Vejsová, M., Kalinowski, D., Kovacevic, Z., Coffey, A.,Csöllei, J., Richardson, Des R., Jampílek, J.: Investigating the Spectrum of Biological Activity of Ring-Substituted Salicylanilides and Carbamoylphenylcarbamates.    
  11. Fajkusová, D., Peško, M., Keltošová, S., Guo, J., Oktábec, Z., Vejsová, M., Kollár, P., Coffey A., Csöllei, J., Kráľová, K., Jampílek, J.: Anti-infective and herbicidal activity of N-substituted 2-           aminobenzothiazoles. Bioorg. Med. Chem. 20, 7059-7068 (2012)